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M94A0344.TXT
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1994-10-08
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Document 0344
DOCN M94A0344
TI Albuminuria in HIV-infected patients.
DT 9412
AU Busch HW; Riechmann S; Heyen P; Heidenreich S; Kaufmann CC; Rahn KH;
Zidek W; Medizinische Poliklinik, Westfaelischen Wilhelms Universitaet;
Muenster, Germany.
SO AIDS Res Hum Retroviruses. 1994 Jun;10(6):717-20. Unique Identifier :
AIDSLINE MED/94355117
AB Albumin excretion, Analysis of urinary proteins by polyacrylamide gel
electrophoresis (PAGE), and clinical evaluation were performed in 90
HIV-infected patients to assess subclinical renal involvement in HIV
infection. Thirteen percent of all patients showed an albumin excretion
> 20 mg/liter. Seven of four homosexual patients had albuminuria.
Albuminuria occurred exclusively with T4 cell counts below 200/mm3.
Polyacrylamide gel electrophoresis indicated glomerular lesions and
showed no tubular proteinuria in patients with increased albumin
excretion. It is concluded that subclinical renal involvement is not
uncommon in HIV infection with T4 cell counts > 200/mm3. HIV-associated
nephropathy and heroin-associated nephropathy may not be the main causes
of renal involvement. In some cases, opportunistic viral infections may
be the cause of microalbuminuria.
DE Adolescence Adult Albuminuria/*COMPLICATIONS/URINE Caucasoid Race
Female Human HIV Infections/*COMPLICATIONS
Kidney/*PHYSIOPATHOLOGY/ULTRASONOGRAPHY Male Middle Age T4
Lymphocytes JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).